陈楠生,研究员/博导,研究方向:海洋基因组学。

教育及工作经历

1984-1989年：复旦大学，本科；

1989-1994年：中国科学院海洋研究所，硕士研究生，博士研究生；

1994-1996年：美国犹他大学，博士后；

1996-2000年：加拿大英属哥伦比亚大学，博士后；

2001-2006年：美国冷泉港实验室，博士后、助理研究员；

2006-2018年：加拿大西蒙菲沙大学，副教授、终身副教授、终身正教授；

2018-现在：中国科学院海洋研究所，研究员。

承担项目情况

作为负责人承担中国科学院百人计划A项目，青岛海洋科学与技术国家实验室主任基金项目。

发表专著情况

《对虾生物学》，Dall等著，陈楠生等译，489页，青岛海洋大学出版社，1992。

发表文章情况

共发表论文80余篇，如下是一些代表性论文。

1. Qin Z, Johnsen R, Yu S, Chu JSC, Baillie DL, and Chen. 2018. Genomic identification and functional characterization of essential genes in Caenorhabditis elegans. G3.

2. Dong L, Liu H, Zhang J, Yang S, Kong G, Chu JS, Chen N, Wang D, 2015. Single-molecule real-time transcript sequencing facilitates common wheat genome annotation and grain transcriptome research. BMC Genomics. 16:1039.

3. Zou S, Li J, Zhou H, Frech C, Jiang X, Chu JS, Zhao X, Li Y, Li Q, Wang H, Hu J, Kong G, Wu M, Ding C, Chen N, Hu H. 2014. Mutational landscape of intrahepatic cholangiocarcinoma. Nature Communications. 5:5696.

4. Uyar B, Chu JSC, Vergara IA, Chua SY, Jones MR, Wong T, Baillie, DL, and Chen N. 2012. RNA-seq analysis of C. briggsae transcriptome. Genome Research, 22(8)1567-1580.

5. Chu JSC, Tarailo-Graovac M, Zhang D, Wang J, Uyar B, Tu D, Trinh J, Baillie DL, and Chen N. 2012. Fine tuning of RFX/DAF-19-regulated target gene expression through binding to multiple sites in Caenorhabditis elegans. Nucleic Acids Research , 40(1):53-64.

6. Frech C and Chen N. 2011. Genome comparison of human and non-human malaria parasites reveals parasites-specific genes potentially linked to human disease. PLoS Computational Biology. 7(12): e1002320.

7. She R*, Chu JSC*, Uyar B, Wang J, Wang K, and Chen N. 2011. genBlastG: using BLAST searches to build homologous gene models. Bioinformatics. 27(15): 2141–2143.

8. She R*, Chu JSC*, Wang K, Pei J, Chen N. 2009. genBlastA: enabling BLAST to identify homologous gene sequences. Genome Research. 19: 143-149.

9. Chen N, Mah A, Blacque OE, Chu J, Phgora K, Khattra J, Chan S, Go A, Efimenko E, Johnsen R, Phirke P, Swoboda P, Marra M, Moerman DG, Leroux MR, Baillie DL, and Stein LD. 2006. Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biology, 7(12):R126.

10. Sea Urchin Genome Sequencing Consortium. 2006. The genome of the sea urchin Strongylocentrotus purpuratus. Science. 314(5801)

11. Chen N, Stein LD. 2006. Conservation and Functional Significance of Gene Topology in the Genome of Caenorhabditis elegans. Genome Research. 16:606-617.

12. Chen N, Pai S, Zhao Z, Mah A, Newbury R, Johnsen RC, Altun Z, Moerman DG, Baillie DL, Stein LD. 2005. Identification of a nematode chemosensory gene family. Proc Natl Acad Sci U S A. 102(1):146-51.

13. Chen N, Harris TW, Antoshechkin I, Bastiani C, Bieri T, Blasiar D, Bradnam K, Canaran P, Chan J, Chen CK, Chen WJ, Cunningham F, Davis P, Kenny E, Kishore R, Lawson D, Lee R, Muller HM, Nakamura C, Pai S, Ozersky P, Petcherski A, Rogers A, Sabo A, Schwarz EM, Van Auken K, Wang Q, Durbin R, Spieth J, Sternberg PW, Stein LD. 2005. WormBase: a comprehensive data resource for Caenorhabditis biology and genomics. Nucleic Acids Research 33(Database issue):D383-9.

14. Chen N, Lawson D, Bradnam K, Harris TW, Stein LD. 2004. WormBase as an integrated platform for the C. elegans ORFeome. Genome Research. 14(10B):2155-61.

15. Stein LD, Bao Z, Blasiar D, Blumenthal T, Brent MR, Chen N, Chinwalla A, Clarke L, Clee C, Coghlan A, Coulson A, D'Eustachio P, Fitch DH, Fulton LA, Fulton RE, Griffiths-Jones S, Harris TW, Hillier LW, Kamath R, Kuwabara PE, Mardis ER, Marra MA, Miner TL, Minx P, Mullikin JC, Plumb RW, Rogers J, Schein JE, Sohrmann M, Spieth J, Stajich JE, Wei C, Willey D, Wilson RK, Durbin R, Waterston RH. 2003. The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biology E45.